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Tinnitus is still very much a mystery with despite all the advances in science. Many theories and hypothesis proposed to explain the origin but still it is poorly understood. Still most common acceptation associated with tinnitus is that it is a type of phantom phenomenon. This article aimed to review tinnitus and our current understanding on definition, types, probable pathophysiological mechanisms, associated trigger factors and current available treatment options.

References

  1. Baguley D, Mcferran D, Hall D. 2013. Tinnitus. Lancet 382, 1600-1602.
     Google Scholar
  2. Kochkin S, Tyler R, Born J. The Prevalence of Tinnitus in the United States and the Self-Reported Efficacy of Various Treatments. Hearing Review. 2011; 18(12): 10–26.
     Google Scholar
  3. Nondahl DM, Cruickshanks KJ, Wiley TL, et al. Prevalence and 5-year Incidence of Tinnitus among Older Adults: The Epidemiology of Hearing Loss Study. J Am Acad Audiol. 2002; 13: 323–331.
     Google Scholar
  4. Shargorodsky J, Curhan GC, Farwell WR. Prevalence and characteristics of tinnitus among US adults. Am J Med. 2010; 123(8): 711–718.
     Google Scholar
  5. Park RJ, Moon JD. Prevalence and risk factors of tinnitus: the Korean National Health and Nutrition Examination Survey 2010–2011, a cross-sectional study. Clin Otolaryngol. 2014; 39(2): 89–94.
     Google Scholar
  6. Jalessi M, Farhadi M, Asghari A, et al. Tinnitus: an epidemiologic study in Iranian population. Acta Med Iran. 2013; 51(12): 886–891.
     Google Scholar
  7. Sindhusake D, Mitchell P, Newall P, et al. Prevalence and characteristics of tinnitus in older adults: The Blue Mountains Hearing Study. Int J Audiol. 2003b; 2003; 42: 289–294.
     Google Scholar
  8. James A. Henry. Progressive Tinnitus Management: Clinical Handbook for Audiologists. 2010.
     Google Scholar
  9. Dietrich S. Earliest historical reference of tinnitus is controversial. J Laryngol Otol. 2004 Jul ;118(7): 487-8.
     Google Scholar
  10. https://www.theatlantic.com/health/archive/2016/01/the-sound-that-comes-from-nowhere/424932/.
     Google Scholar
  11. https://www.hands-free.co.uk/a-history-of-tinnitus/.
     Google Scholar
  12. Dauman R., & Tyler R. S. (1992). Some considerations on the classification of tinnitus. In Aran J.-M., & Dauman R. (Eds.), Proceedings of the Fourth International Tinnitus Seminar, Bordeaux, France (pp. 225–229). Amsterdam, the Netherlands: Kugler.
     Google Scholar
  13. Schlee, W., Weisz, N., Bertrand, O., Hartmann, T., and Elbert, T. (2008). Using auditory steady state responses to outline the functional connectivity in the tinnitus brain.
     Google Scholar
  14. Tunkel, D. E., Bauer, C. A., Sun, G. H., Rosenfeld, R. M., Chandrasekhar, S. S., Cunningham, E. R., et al. (2014). Clinical practice guideline: tinnitus. Otolaryngol. Head Neck Surg. 151, S1–S40.
     Google Scholar
  15. Michiels, S., Ganz Sanchez, T., Oron, Y., Gilles, A., Haider, H. F., Erlandsson, S., et al. (2018). Diagnostic criteria for somatosensory tinnitus: a delphi process and face-to-face meeting to establish consensus. Trends Hear. 22:2331216518796403.
     Google Scholar
  16. Henry, J. A., Roberts, L. E., Caspary, D. M., Theodoroff, S. M., and Salvi, R. J. (2014). Underlying mechanisms of tinnitus: review and clinical implications. J. Am. Acad. Audiol. 25, 5–22; quiz 126.
     Google Scholar
  17. Byung In Han, Ho Won Lee, Tae You Kim, Jun Seong Li, Kyoung Sik Shin. Tinnitus: Characteristics, Causes, mechanisms, Treatments. J Clin Neurol. 2009 Mar; 5(1): 11-19.
     Google Scholar
  18. Kemp DT. Physiologically active cochlear micromechanics--one source of tinnitus. Ciba Found Symp. 1981; 85: 54–81.
     Google Scholar
  19. Kiang NY, Moxon EC, Levine RA. Auditory-nerve activity in cats with normal and abnormal cochleas. In: Sensorineural hearing loss. Ciba Found Symp. 1970: 241–273.
     Google Scholar
  20. Baguley DM. Mechanisms of tinnitus. Br Med Bull. 2002; 63: 195–212.
     Google Scholar
  21. https://www1.racgp.org.au/ajgp/2018/april/tinnitus/.
     Google Scholar
  22. https://www.ata.org/understanding-facts/causes.
     Google Scholar
  23. Nuttal AL, Meikle MB, Trune DR. Peripheral process involved in tinnitus. In: Snow JB, editor. Tinnitus: theory and management. Ontario: BC Decker; 2004. pp. 52–68.
     Google Scholar
  24. https://bpac.org.nz/BPJ/2012/october/tinnitus.aspx.
     Google Scholar
  25. Eric Hofmann, Robert Behr, Tobias Neumann-Hafelin, Konrad Schwager. Pulsatile Tinnitus. Dtsch Arztebl Int. 2013 Jun; 110(26): 451-458.
     Google Scholar
  26. Hall, D. A., Fackrell, K., Li, A. B., Thavayogan, R., Smith, S., Kennedy. (2018). A narrative synthesis of research evidence for tinnitus-related complaints as reported by patients and their significant others. Health and Quality of Life Outcomes, 16(1), 61.
     Google Scholar
  27. Pierce, K. J., Kallogjeri, D., Piccirillo, J. F., Garcia, K. S., Nicklaus, J. E., & Burton, H. (2012). Effects of severe bothersome tinnitus on cognitive function measured with standardized tests. Journal of Clinical and Experimental Neuropsychology, 34(2), 126–134.
     Google Scholar
  28. Nondahl, D. M., Cruickshanks, K. J., Dalton, D. S., Klein, B. E., Klein, R., Schubert, C. R., & Wiley, T. L. (2007). The impact of tinnitus on quality of life in older adults. Journal of the American Academy of Audiology, 18(3), 257–266.
     Google Scholar
  29. Langguth, B., & Landgrebe, M. (2011). Tinnitus and depression. Textbook of Tinnitus, 2975(May), 493–498.
     Google Scholar
  30. Emily J Watts, Kathryn Fackrell, Sandra Smith, Jacqueline Sheldrake, Haula Haider, Derek J Hoare. Why Is Tinnitus a Problem? A qualitative Analysis of Problems Reported by Tinnitus Patients. Trends in Hearing. Volume 22: 1-10.
     Google Scholar
  31. Dongmei Tang, Huawei Li, Lin Chen. Advances in Understanding, Diagnosis and Treatment of Tinnitus. Adv Exp Med Biol. 2019; 1130: 109-128.
     Google Scholar
  32. Byung In Han, Ho Won Lee, Tae You Kim, Jun Seong Lim, Kyoung Sik Shin. Tinnitus: Characteristics, Causes, Mechanisms, and Treatments. J Clin Neurol 2009; 5: 11-19.
     Google Scholar
  33. Henry JA, Zaugg TL, Myers PM, et al. Progressive Tinnitus Management: Clinical Handbook for Audiologists. San Diego, Calif: Plural Publishing; 2010.
     Google Scholar
  34. Tyler RS, ed. Tinnitus Treatment: Clinical Protocols. New York: Thieme Medical Publishers, Inc; 2005.
     Google Scholar
  35. Vernon JA. Tinnitus Treatment and Relief. Needham Heights, Mass: Allyn & Bacon; 1998.
     Google Scholar
  36. Jastreboff PJ, Hazell JWP. Tinnitus Retraining Therapy: Implementing the Neurophysiological Model. New York: Cambridge University Press; 2004.
     Google Scholar
  37. Magdalena Sereda, Jun Xia, Amr Al Refaie, Deborah A Hall, Derek J Hoare. Cochrane Database Syst Review. 2018 Dec 2018(120.
     Google Scholar
  38. Thomas Fuller, Rilana Cima, Berthold Langguth, Birgit Mazurek, Johan WS Vlaeyen, Derek J Hoare. Cognitive Behavioural Therapy for Tinnitus. Cochrane Database Syst Rev. 2020 Jan; 2020(1).
     Google Scholar
  39. Department of Health. Provision of Services for Adults with Tinnitus. A Good Practice Guide. London: Central Office of Information, 2009.
     Google Scholar
  40. Tunkel DE, Bauer CA, Sun GH, Rosenfeld RM, Chandrasekhar SS, Cunningham ER Jr, et al. Clinical practice guideline: tinnitus executive summary. Otolaryngology‐‐Head and Neck Surgery 2014; 151(4): 533‐41.
     Google Scholar
  41. Maggie Kuhn, Selena E, Heman Ackah, Jamil A Shaikh, Pamela C Roehm. Sudden Sensorineural Hearing Loss: A review of Diagnosis, Treatment, and Prognosis.
     Google Scholar
  42. Jayakumar A, et al. Treatment of idiopathic sudden sensorineural hearing loss. Acta Otolaryngol. 2006; 126: 708-713.
     Google Scholar
  43. Sismanis A. Pulsatile tinnitus. Otolaryngol Clin North Am. 2003; 36: 389-402.
     Google Scholar
  44. Lockwood AH, Burkard RF, Salvi RJ. Imaging tinnitus. In: Snow JB, ed. Tinnitus: Theory and Management. Lewiston, NY: BC Decker Inc; 2004: 253-264.
     Google Scholar
  45. Charlotte Agrup, Michael Gleeson, Peter Rudge. The inner ear and neurologist. J Neurol Neurosurg Psychiatry. 2007 Feb; 78(20): 114-122.
     Google Scholar
  46. Massimo Ralli, Vittorio D’Aguanno, et al. Audiovestibular Symptoms in Systemic Autoimmune Diseases. Journal of Immunology Research. 19 Aug 2018.
     Google Scholar
  47. Traian S Ataman. Cholesteatoma of the Tympanic Part of the Temporal Bone. International Tinnitus Journal, Vol. 13, No. 1, 45-48 (2007).
     Google Scholar
  48. Seidu A Richard. Li Qiang, Zhi Gang Lan, Yuekang Zhang, Chao You. A giant cholesteatoma of the mastoid extending into foramen magnum: A case report and review of literature.
     Google Scholar
  49. Djalilian, Hamid R. Symptoms: Hearing Loss and Facial Paralysis. The Hearing Journal. May 2014, Volume 67, Issue 5, p. 11-14.
     Google Scholar
  50. Watanabe I, Kumagami H, Tsuda Y. An Abnormal Phenomenon in the Course of Facial Nerve Paralysis and its Audiological Significance. ORL 1974; 36: 217-226.
     Google Scholar
  51. Xiang Huang, Jian Xu, Lian-Fu Zhou, Rong Zhang, et al. Clinical features of intracranial vestibular schwannoma. Oncology Letters. January 2013, Volume 5 Issue 1.
     Google Scholar
  52. Angelica A Nunez, Luis R Ramos-Duran, Albert C Cuetter. Glomus Jugulare Presenting isolated facial Nerve Palsy. Surgery Research and Practice. Volume 2014, Article ID 514086, 3 pages.
     Google Scholar
  53. Newman CW, Sandridge SA, Jacobson GP. Psychometric adequacy of the Tinnitus Handicap Inventory (THI) for evaluating treatment outcome. J Am Acad Audiol. 1998; 9:153-160.
     Google Scholar
  54. Abby McCormack, Mark Edmondson-Jones, Heather Fortnum, et al. Investigating the association between tinnitus severity and symptoms of depression and anxiety, while controlling for neuroticism, in a large middle-aged UK population.
     Google Scholar
  55. House JW, Brackmann DE. Tinnitus: surgical treatment. Ciba Foundation Symposium 1981; 85: 204–216.
     Google Scholar
  56. Teo Soleymani, Peter Pieton, Patrick Pezeshkian, Patrick Miller, et al. Surgical approaches to tinnitus treatment: A review and novel approaches. Surgical Neurology International. 2011; 2-154.
     Google Scholar
  57. David J Eisenman, Taylor B Teplitzky. Neuroimaging Clinics. Volume 26, Issue 2, P279-288, May 1, 2016.
     Google Scholar
  58. Paul Van de Heyning, Dirk de Ridder, Karolien Van der Kelen, et al. Surgical treatment of tinnitus. Audiological Medicine. 2004; 2: 83-87.
     Google Scholar
  59. Park J, White AR, Ernst E. Efficacy of acupuncture as a treatment for tinnitus: A systematic review. Archives of Otolaryngology— Head & Neck Surgery 2000; 126(4): 489–492.
     Google Scholar
  60. Dobie RA. A review of randomized clinical trials in tinnitus. Laryngoscope 1999;109(8):1202–1211.
     Google Scholar
  61. Smith JA, Mennemeier M, Bartel T, Chelette KC, Kimbrell T, Triggs W, Dornhoffer JL. Repetitive transcranial magnetic stimulation for tinnitus: a pilot study. Laryngoscope 2007; 117(3): 529–534.
     Google Scholar